ABDERRAHIM Benslama
بن سلامة عبدالرحيم
abderrahim.benslama@univ-msila.dz
06 61 00 00 00
- Departement of Microbiology and biochemistry
- Faculty of Sciences
- Grade MCA
About Me
Location
Msila, Msila
Msila, ALGERIA
Code RFIDE- 2023
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Encaderement master
CHEBABHA Chahira , CHABI Ibtissam, MAKHLOUF Farida
Etude de l’activité antibactérienne des champignons endophytes isolé de Retama retam
- 2023
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Encaderement master
Benzemmouri Kheira , Guemra Lina Loudjeyne, Khezzari Khaoula
Étude de l’activité antioxydante et antibactérienne de propolis
- 2023
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Encaderement master
BEN NACEIR Chahinez , BAATOUCHE Chahinez, BOUABDALLAH Dounya
Essai d’élaboration d’un yaourt fonctionnel sucré par la poudre des graines de caroube
- 2022
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Encaderement master
Gasri Fatiha , Hamadi Safa
Evaluation de l’activité antioxydante de l’extrait méthanolique de la plante Genista quadriflora
- 2022
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Encaderement master
DELLALI SAADIA , TORCHI IMANE
Etude ethnopharmacologique et phytochimique de pallenis spinosa
- 2021
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Encaderement master
Zoubida Charef , Amina Himeur
Evaluation de l’activité antioxydante des extraits d’Ammi visnaga
- 2021
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Encaderement master
Kharfi Nour Elimane , Rezgui Khouloud
L’effet de pasteurisation sur les caractéristiques physicochimiques et microbiologiques de lait de vache
- 2021
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Encaderement master
Lekhel Nadjette
Polyphénols totaux et activité antibactérienne des extraits de la plante médicinale Ammi visnaga L.
- 2019
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Encaderement master
Zouid Imen , Mokarne El-Roumayssa
Évaluation de l'activité antibactérienne des extraits de quatre plantes médicinales
- 2019
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Encaderement master
CHIRANE Aymene , MERZOUD Youssouf
Evaluation de l’activité antibactérienne des champignons endophytes isolés à partir Artemisia herba alba
- 1987-05-22 00:00:00
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ABDERRAHIM Benslama birthday
- 2023-06-17
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2023-06-17
Ethnopharmacology, Phytochemistry, and Pharmacology of Santolina rosmarinifolia: A review
Medicinal plants have played an important influence in the development of human society; they were always at the forefront of all cultures and civilizations as a source of medicine. Medicinal plants are considered rich sources of secondary compounds, and many modern medications are derived from them. Santolina is the most diverse genus within the mint family (Asteraceae), that is widely distributed in the Mediterranean basin and many of its species are well-known due to their medicinal and culinary uses. The present research discusses the traditional uses, phytochemical components and biological activities of Santolina rosmarinifolia. To do so, we carried out a comprehensive review of the articles available in different online databases published from the past to 2022 (i.e., PubMed, Scopus, and Web of Science, among others). S. rosmarinifolia has several traditional uses, including as anti-inflammatory and an antimicrobial agent, among several others, ascribed to it. In Spain, S. rosmarinifolia’s flowerheads are traditionally used as antipyretic, anti-inflammatory, antihypertensive and hepatoprotective. In Algeria, this plant is used for the treatment of dermatoses. The same uses are also reported in Portugal. The phytochemical studies have revealed the presence of terpenes, including monoterpenes, eudesmane-type sesquiterpenes, germacrene-type sesquiterpenes, dammarane-type triterpenes, coumarins, and flavonoids as the main classes of constituents. A study carried out on santolina Essential oil showed existence of sabinene, β-pinene, myrcene, β-phellandrene, limonene, 1,8-cineole, artemisia ketone, terpinen-4-ol, capillene, ar-curcumene and β-eudesmol. Monoterpenes like β- phellandrene, limonene and 1,8-cineole are also identified. In conclusion, this studys provides much information about the interests of vegetal species: Santolina rosmarinifolia.
Citation
Asma Medjahed , Abderrahim BENSLAMA , ,(2023-06-17), Ethnopharmacology, Phytochemistry, and Pharmacology of Santolina rosmarinifolia: A review,Séminaire National sur : Biodiversité, Santé et Environnement,Université de Temcen
- 2023-05-26
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2023-05-26
Algerian medicinal plants : Traditional Uses, Phytochemistry and Pharmacological Activities
Algerian medicinal plants : Traditional Uses, Phytochemistry and Pharmacological Activities
Citation
Abderrahim BENSLAMA , ,(2023-05-26), Algerian medicinal plants : Traditional Uses, Phytochemistry and Pharmacological Activities,Current Drug Research Topics in Pharmacy: Traditional Medicine Talks,Turquie
- 2023-05-04
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2023-05-04
Activité anti-inflammatoire de quelques plantes médicinales de Kabylie
Les molécules à usage anti-inflammatoire commercialisées en Algérie au jour d'aujourd'hui, à l'instar de l'ibuprofène, causent bon nombre de pathologies en raison de leurs nombreux effets secondaires à posologie usuelle et en administration percutanée (complications cardio-pulmonaires, hypertension artérielle, insuffisance rénale). L'Algérie de part sa grande superficie et ses variations climatiques, donne lieu à une variabilité et une diversité des espèces végétales. Ajoutant à cela que notre pays riche de son patrimoine traditions, nous offre un éventail important et différent de l'usage médicinal fait de ces plantes. Les molécules bioactives issues de ces plantes, suscitent actuellement un intérêt grandissant dans les domaines pharmaceutique. Le regain d’intérêt en thérapeutique pour ces biomolécules est motivé par le fait qu’elles présentent des effets secondaires limités ou inexistants comparativement aux molécules synthétiques qui en plus de causer de nombreux effets secondaires indésirables présentent des limites thérapeutiques. Notre étude, qui s’inscrit dans l’optique de valorisation des ressources végétales, a pour objectif, l’évaluation du potentiel anti-inflammatoire de quelques plantes médicinales de Kabylie (carthamus caeruleus, Rosa sempervirens, Lavandula stoechas, Romarinus officinalis, Malva sylvestris, Arbutus unedo). L’appréciation de la capacité anti-inflammatoire des plantes étudiées, a été effectué par le test de stabilisateur des membranes érythrocytaires vis-à-vis de différents stress (osmotique, oxydant induit par le HOCL et la chaleur) et par la stabilisation thermique de la sérum albumine. La somme des résultats obtenus au cours de cette étude montre clairement que les extraits aqueux de feuilles des plantes étudiées, possèdent un potentiel anti-inflammatoire important. De ce fait, ces plantes constituent une source potentielle de molécules bioactives et ainsi constituent une alternative thérapeutique au traitement de nombreuses pathologies initiées par le stress oxydant.
Citation
Abderrahim BENSLAMA , Mk idir, Beunis yussra, ,(2023-05-04), Activité anti-inflammatoire de quelques plantes médicinales de Kabylie,International Seminar on Bioresources and Sustainable Development,Université de Bouira
- 2022
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2022
Phytochemical analysis, Antibacterial effect and the antioxidant activity of Atriplex halumus extracts
Phytochemical analysis, Antibacterial effect and the antioxidant activity of Atriplex halumus extracts
Citation
Abderrahim BENSLAMA , ,(2022), Phytochemical analysis, Antibacterial effect and the antioxidant activity of Atriplex halumus extracts,International Online Conference on Valuation of Alternative Plants, Degraded & Margin,Université, EL- OUED
- 2022
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2022
Activité anti-inflammatoire et antioxydante de citron (Citrus limon)
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Citation
Abderrahim BENSLAMA , ,(2022), Activité anti-inflammatoire et antioxydante de citron (Citrus limon),Journées scientifique Biodiversité , santé et environnement,Université de Bouira
- 2021
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2021
Isolation, identification and antibacterial activity of endophytic fungi from Marrubium vulgare L
Isolation, identification and antibacterial activity of endophytic fungi from Marrubium vulgare L
Citation
Abderrahim BENSLAMA , ,(2021), Isolation, identification and antibacterial activity of endophytic fungi from Marrubium vulgare L,Séminaire national : Bio-ressources: Nutrition, Santé et Environnement.,Université de M'sila
- 2017
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2017
Phenolic Compounds, Antioxidant and Antibacterial Activities of Zizyphus lotus L. Leaves Extracts
Background: The use of plants for the treatment, cure and prevention of diseases is one of the oldest medicinal practices of humanity. These plants are able to produce much diversified natural compounds (e.g. alkaloids, polyphenols, etc.) which have many pharmaceutical applications. Objective: The aim of the present study was to evaluate the antioxidant capacity and antibacterial activity of Zizyphus lotus extracts, which has been used traditionally in folk medicine of Algeria. Methods: The leaves of plants were submitted to extraction by water and methanol to give methanolic (Met.E) and aqueous (Aq.E). The extracts were analyzed by HPLC-TOF/MS and their antioxidant activity was determined using DPPH and ABTS free radical-scavenging test, when the antibacterial activity was determined using disc diffusion method. Results: The quantitative analysis of polyphenols and flavonoids content showed that the Met.E had the highest amount (562.04 µg EAG/mg E and 66.34 µg EQ/mg E, respectively). The HPLC-TOF/MS analysis of Met.E reveals the presence of two major compounds, rutin and gentisic acid, when Aq.E contain rutin and quercetin-3-β-D-glucoside as a major compound. Results showed that the Met.E exhibited the highest antiradical activity against DPPH and ABTS free radical with EC50=28.19±0.51 µg/mL, and EC50=3.82±0.03 µg/mL, respectively. Moreover, the Met. E of Z. lotus presents a moderate antibacterial activity against Staphylococcus aureus, Micrococcus luteus and Bacillus subtilis, with inhibition zone ranging from 09 to 13 mm. In addition, The Met.E showed a better MIC against M. luteus and B. subtilis (MIC= 25 µg/mL). Conclusion: Our results showed that the methanolic extract of Z. lotus reported a considerable antioxidant and antibacterial activities which may be due to their richness on polyphenols and flavonoids. Keywords: Antioxidant, antibacterial, Z. lotus, phenolic compounds, HPLC-TOF/MS, disc diffusion method, methanolic (Met.E) extract.
Citation
Abderrahim BENSLAMA , Abdenassar HARRAR , Fatih GÜL, Ibrahim DEMİRTAŞ, , (2017), Phenolic Compounds, Antioxidant and Antibacterial Activities of Zizyphus lotus L. Leaves Extracts, The Natural Products Journal, Vol:7, Issue:4, pages:1-7, Bentham science
- 2017
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2017
Acute, sub-acute toxicity and antioxidant activities (in vitro and in vivo) of Reichardia picroide crude extract
Ethnopharmacological relevance: Reichardia picroide is a species mainly used for alimentary purposes, but it is traditionally known to be used as hypoglycemiant, diuretic, depurative, galactagogue and tonic. Aim of the study: To date, there are no studies corroborating both its safety and antioxidant activities. The objective of the present study, thus, was to assess the safety profile of Reichardia picroide methanolic extract (RPE) and as well as on its antioxidant and antihemolytic activities. Materials and methods: The acute toxicity of RPE was carried out based on OECD guidelines 425. Signs accompanying toxicity and possible death of animals were monitored for two weeks to ascertain the medianlethal dose (LD50) of the RPE. In sub-acute toxicity study, the extract was administered by gavage at the doses of 250, 500 and 1000 mg/kg/day for 21 consecutive days. The antioxidant activity of RPE was investigated through various methods both in vitro and in vivo. Results: The admistrated doses did not produce mortality or changes in general behaviors of the tested males and females mice. The LD50 was found to be superior to 5000 mg/kg DW. Moreover, daily administration of RPE at doses ranged from 500 to 1000 mg/kg could result in alteration of liver and kidney histology. Significant decrease in liver enzymes (ALT and AST), urea and creatinine levels in female plasma was recorded. The RPE was, in vitro, strong in DPPH scavenging and hemolytic inhibition, benificial in lipid peroxidation inhibition and reducing power. In addition, it exhibited, in vivo, a strong effect on GSH level increasing and lipid peroxidation inhibition in liver and kidney. Conclusions: It can be suggested, based on the results of this study, that the crude extract of Reichardia picroide was non-toxic in acute administration and the use of this extract is safe at doses ≤ 250 mg/kg. This study supports the application of Reichardia picroides in alimentary and traditional medicine purposes. Moreover, antioxidant activity results suggested that Reichardia picroide had potent antioxidant activities and could be utilized as new natural antioxidant in food and therapeutics.
Citation
Abderrahim BENSLAMA , Sana AOUACHRIA, Sabah BOUMERFEG, Fayçal BENBACHA, Thorya GUEMMAZ, , (2017), Acute, sub-acute toxicity and antioxidant activities (in vitro and in vivo) of Reichardia picroide crude extract, Journal of Ethnopharmacology, Vol:2017, Issue:208, pages:105-116., Elsevier
- 2016
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2016
Free radicals scavenging activity and reducing power of two Algerian Sahara medicinal plants extracts.
The aim of this study is to evaluate antioxidant activity of aqueous (Aq.E) and methanolic (Met.E) extracts of Zygophyllum album L. (Zygophyllaceae) and Arthrophytum scoparium (Chenpodiacea), two medicinal plant from Algerian Sahara used in traditional pharmacopoeia. The results showed that Aq.E have the heights yields 24% and 22.3% for Z. album and A. scoparium respectively. Qualitative analysis of showed that the Met.E of Z. album of had the highest amount of polyphenols (202.26±4.73 µg GAE/mg E) and flavonoids (15.77±0.94 µg QE/mg E). The antioxidant activity of extracts was evaluated by 2, 2’-diphenyl-1-picrylhydrazyl (DPPH) and reducing power assay. Results showed that the extracts of A. scoparium. Have the highest free radical scavenger activity in DPPH test (EC50=0.096±0.001 and 0.108±0.002 mg/ml for Met.E and Aq.E respectively). In addition, the results of reducing power assay demonstrated that Met.E of Z. album had the highest effect with 2399.65±12.31 µg ascorbic acid equivalent/mg E.Our results showed that the methanolic extract reported a considerable free radicals scavenging activity and reducing effect, may be due to their richness on polyphenols and flavonoids.
Citation
Abderrahim BENSLAMA , abdenassar.harrara@univ-msila.dz, , (2016), Free radicals scavenging activity and reducing power of two Algerian Sahara medicinal plants extracts., International Journal of Herbal Medicine, Vol:4, Issue:6, pages:158-161, Akhil Gupta
- 2016
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2016
Total phenolic contents, antioxidant and antibacterial activities of Limoniastrum guyonianum (Plombaginaceae) extracts
This work was carried out to study the antioxidant capacity and antibacterial activity of Limoniastrum guyonianum (Plombaginaceae) extracts, traditionally used in folk medicine in Algeria. The aerial part were submitted to extraction by water and methanol to give methanolic (Met.E) and aqueous (Aq.E) extracts with that yields are 10%and 17,5% respectively. Quantitative analysis of polyphenols and flavonoids content showed that the Met. E had the highest amount (285.37µg EAG/mgE and 44.11µg EQ/mg E, respectively). The antioxidant activity of extracts was evaluated by 2,2’-diphenyl-1-picrylhydrazyl (DPPH) and ABTS free radical-scavenging test. Results showed that the Met. E exhibited the highest antiradical activity against DPPH and ABTS free radical with EC50=0,099 mg/ml, and EC50=0.024mg/ml, respectively. Moreover, the antibacterial activity was determined on the five bacterial strains, using disk diffusion method. The Met. E showed inhibition zone averages only on M. luteus, and S. aureus (12 and 13 mm respectively) and with MIC is 25 μg/ml. Our results showed that the methanolic extract of L. guyonianum reported a considerable antioxidant and antibacterial activities which may be due to their richness on polyphenols and flavonoids.
Citation
Abderrahim BENSLAMA , Abdenassar HARRAR , Safia AFISSA, Asma SAIDI, , (2016), Total phenolic contents, antioxidant and antibacterial activities of Limoniastrum guyonianum (Plombaginaceae) extracts, International Journal of Current Research, Vol:2016, Issue:812, pages:42675-42679, akhil kapio