Background: The genus Physalis was first found by Linnaeusin 1753, withnin especies. However, two of the nine species are now known as Withania. Physalis species have been used in Asian and American folk medicine to treat a variety of ailments such as cancer, leukemia, dermatitis, asthma, malaria, liver disorders, and as an immunomodulatory agent. For these reasons, our work is focused on phytochemical and biological studies of the Physalis genus.
Materials and methods: As a first step, our study used a face-centered central composite design (CCDC) to generate surface responses and ultrasound bath equipment to optimize three parameters (extraction time, ratio liquid/solid, and solvent concentration) to obtain the best extraction conditions, influencing total bioactive content (TPC, TFC) as well as total antioxidant activity (TAC).
Results: According to our experimental design results, the highest values of responses (TPC, TFC, and TAC) were obtained under the following conditions: 70% ethanol concentration, 60 minutes of extraction time, and a 10:1 dry weight of plant ratio.
Conclusion: As a result, it appears reasonable to believe that optimized ultrasonic extraction could be successfully applied to maximize the yield of antioxidant polyphenols from Physalis species.
Citation
LARBI Derbak ,
HAMDI Bendif ,
Khellaf BELKHIRI ,
AYAD Radia, SOUILAH Nabila, ,(2022), Optimization of Ultrasound assisted of antioxidant phenolics extraction from an Algerian physalis species,International Seminar on Valorization of Agronomic, Ecological and Food Resources,University of Skikda