Introduction: Verbascum L. is the largest genus of the Scrophulariaceae family,
which comprises more than 300 species of wild growing plants, Verbascum betonicifolium (V. betonicifolium) is a plant used in traditional medicine for several ailments. The objective of this study was to determine the first phytochemical characterization of aqueous extracts from aerial parts. Methods: The compounds present in the aerial part aqueous extract were identified by high performance liquid chromatography, coupled to a diode-array detector (HPLC-DAD) and by high-resolution mass spectrometry (HRMS), using LC–MS/MS analyses. Results: Six types of plant metabolites were found: primary metabolites like malic, gluconic and citric acids, representing 36 % of the identified compounds; secondary metabolites like flavonoid derivatives (apigenin, luteolin) and several glycosylated derivatives, representing 27 % of the identified compounds; caffeic acid derivatives (chlorogenic acid) and several flavonoid derivatives representing 9 % of the identified compounds; iridoids like methylscutelloside, scropheanoside, saccatoside and so on, representing 30 % of the identified compounds; one lignan and a lactone sesquiterpenoid were also tentatively suggested.Conclusions: These results show for the first time the richness of phytochemicals of V. betonicifolium and that the aqueous extract could be used as new natural sources of bioactive molecules.
Citation
HAMDI Bendif ,
Hanane KHALFA ,
Nabila ADOUI ,
Karim MERABTI ,
LARBI Derbak ,
Imane Haouame ,
,(2023), IRIDOIDS AND FLAVONOIDS PRESENT IN DECOCTIONS FROM AERIAL PARTS OF VERBASCUM BETONICIFOLIUM,Séminaire national sur Les Substances Bioactives (SBIO-2023) 14 Mars 2023,univ de ghardaia